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Tramadol and its metabolite, O-desmethyltramadol (M1), are present in human milk. There is absolutely no info on the effects on the drug over the breastfed toddler or the consequences in the drug on milk creation. The M1 metabolite is much more potent than tramadol in mu opioid receptor binding [see https://codeine-phosphate-30mg84826.liberty-blog.com/37547048/the-best-side-of-tramadol-100mg-tablet-price

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