Lousy/Extensive Metabolizers, CYP2D6 The development of the Energetic metabolite, M1, is mediated by CYP2D6, a polymorphic enzyme. Roughly seven% from the population has decreased exercise with the CYP2D6 isoenzyme of cytochrome P450 metabolizing enzyme procedure. These individuals are “bad metabolizers” of debrisoquine, dextromethorphan and tricyclic antidepressants, between other dr... https://stephenu109isy8.fliplife-wiki.com/user