Inadequate/Substantial Metabolizers, CYP2D6 The formation on the active metabolite, M1, is mediated by CYP2D6, a polymorphic enzyme. About seven% on the population has lessened action in the CYP2D6 isoenzyme of cytochrome P450 metabolizing enzyme process. These men and women are “inadequate metabolizers” of debrisoquine, dextromethorphan and tricyclic antidepressants, amid other https://davidm642nvb8.vidublog.com/profile