THCA are unable to activate CB1 receptors without first going through decarboxylation, a system triggered by warmth. As opposed to THCA, THC binds to these receptors and creates psychoactive effects. This really is why smoking cigarettes, vaping, or cooking THCA bud converts it into THC, that's accountable for the “large.” https://thcagoodhealthbenefits55555.mdkblog.com/39889400/not-known-factual-statements-about-cold-cured-cannabis