There's a launch of norepinephrine from the descending inhibitory bulbospinal neurons that binds to alpha-two-receptors within the dorsal horn to reduce afferent pain transmission and develop analgesia. For that reason, medicine like clonidine that target alpha-two receptors can influence the transmission of suffering. Applies to clonidine: oral tablet, oral https://douglasc837tpj7.illawiki.com/user