Environmental or self-antigens and homotypic interactions bring about BCR and Toll-like receptor (TLR) signaling, amplifying the response of CLL cells to other alerts with the microenvironment and raising the activation of anti-apoptotic and proliferation pathways. 102 However, various teams are advocating for the incorporation of novel markers, for instance a https://annq641nvc9.iamthewiki.com/user