Clinicaltrials.gov was searched for registered review protocols. The key terms “palmitoylethanolamide” and “pain” resulted in thirteen entries, of which 3 were completed. None of them fulfilled our eligibility standards. Now, we report the in vitro and in vivo findings, along with medical effects, supporting the probable purpose of ALIAmides, https://garrettupnqo.imblogs.net/80463845/the-greatest-guide-to-palmitoylethanolamide